Tolerance to biodegraded crude oil in marine invertebrate embryos and larvae is associated with expression of a multixenobiotic resistance transporter.

Expression analysis of K+ transporter genes associated with salinity tolerance in grape

Molecular information of K+ accumulation in grapes is strongly required. Under salinity condition potassium transporters are inhibited by Na+. The aim of this study was to investigate the effects of salinity on the expression of K+ transporter genes in grape. Based on the previous screening study on 18 grape genotypes, ‘H6’ and ‘Gharashani’ (tolerant) and ‘Shirazi’ and ‘GhezelUzum’ (sensitive) ...

Unexpected Interaction with Dispersed Crude Oil Droplets Drives Severe Toxicity in Atlantic Haddock Embryos

The toxicity resulting from exposure to oil droplets in marine fish embryos and larvae is still subject for debate. The most detailed studies have investigated the effects of water-dissolved components of crude oil in water accommodated fractions (WAFs) that lack bulk oil droplets. Although exposure to dissolved petroleum compounds alone is sufficient to cause the characteristic developmental t...

The role of multixenobiotic transporters in predatory marine molluscs as counter-defense mechanisms against dietary allelochemicals.

Multixenobiotic transporters have been extensively studied for their ability to modulate the disposition and toxicity of pharmacological agents, yet their influence in regulating the levels of dietary toxins within marine consumers has only recently been explored. This study presents functional and molecular evidence for multixenobiotic transporter-mediated efflux activity and expression in the...

Effects of Biologically Degraded Oil on Marine Invertebrate and Vertebrate Embryos and Larvae

Cytogenetic damage induced by crude oil in Anodonta cygnea (mollusca,bivalvia) assessed by the comet assay and micronucleus test

Crude oil is enriched in polycyclic aromatic hydrocarbons (PAHs). Many PAH analogs have proved to potentially damage DNA. DNA damage can be assessed using various biomarkers to find out the degree of genotoxicity of pollutants following in vitro exposure. In this research the comet assay and micronucleus (MN) test were used to detect DNA damages and cytogenetic changes following crude oil expos...